Desmoplastic melanoma: C>Ts and NF‐ κ B
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چکیده
منابع مشابه
Desmoplastic melanoma: C>Ts and NF‐κB
The past 5 years have seen a paradigm shift in the survival of patients with advanced melanoma, owed in large part to an improved understanding of the genomic complexity of the disease and the development of novel therapies. Large international efforts to systematically sequence tumours have uncovered molecularly discrete subtypes of melanoma, with mutational characteristics found to segregate ...
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Desmoplastic melanoma is a rare variant of spindle cell melanoma that was first described in 1971 by Conley et al. [1] . Between 1988 and 2006, less than 2,000 patients were diagnosed with desmoplastic melanoma in the United States. It accounts for between 1 to 4 percent of all cases of cutaneous melanomas. [2] Early diagnosis of desmoplastic melanoma can often result in favorable outcomes due ...
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Conley et al., in 1971, described a special type of melanoma characterized by a superficial melanic lesion at the onset; repeated local relapses as subcutaneous tumorations with an histological picture closely resembling an atypical fibroxantoma or fibrosarcoma. After a review of all the published material the autors presents a personal case with the clinical, histological and evolutive charact...
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ژورنال
عنوان ژورنال: Pigment Cell & Melanoma Research
سال: 2016
ISSN: 1755-1471,1755-148X
DOI: 10.1111/pcmr.12451